Image

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

Study for mitral valve treatment in patients aged 60 and older.

Recruiting
65 years and older
All
Phase N/A

This study is for people aged 60 and above with a heart problem called mitral regurgitation (MR). MR happens when the mitral valve in the heart doesn't close tightly, causing blood to flow backward. The study compares two treatments: *transcatheter edge-to-edge repair (TEER)*, which fixes the valve without major surgery, and surgical repair, which involves open-heart surgery. Both treatments aim to fix the valve and improve life quality.

The study will take place in the U.S., Canada, Germany, and the UK and will last 5 years. Patients will be checked for up to 10 years. It is for adults with severe MR who can have either TEER or surgery. TEER is still being studied, so it is not fully approved for everyone yet.

Key Points:
  • The study lasts for up to 10 years with regular follow-ups.
  • Both TEER and surgical repair are possible treatments being compared.
  • Participants must be adults with specific heart conditions to join.

This research will help find out which treatment is safer and more effective for people with MR.

Study details
    Mitral Valve Regurgitation

NCT05051033

Annetine Gelijns

8 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.