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A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Join a study for recurrent low-grade serous ovarian cancer treatment.

Recruiting
18 years and older
Female
Phase 3

This study looks at how safe and effective two drugs, avutometinib (VS-6766) and defactinib (VS-6063), are for patients with a type of cancer called Low-Grade Serous Ovarian Cancer (LGSOC) that has come back after treatment. These drugs are kinase inhibitors, which help stop cancer cells from growing. The study compares this combination with other treatments chosen by doctors, to see which helps patients live longer without the cancer getting worse. This is a Phase 3 study, which means it’s in the last stage before a drug might get approved. Patients in the study will either receive the new drug combination or one of the five standard treatments. If the standard treatment doesn’t work, they might switch to the new combination.

  • The study involves regular visits and follow-ups.
  • Participants must be willing to use birth control if they can have children.
  • The drugs are not yet approved by the U.S. Food and Drug Administration (FDA).
Study details
    Low Grade Serous Ovarian Cancer

NCT06072781

Verastem, Inc.

15 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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