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A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

Evaluating XmAb20717 for advanced gynecologic and genitourinary cancers.

Recruiting
18 years and older
All
Phase 2

This study looks at how a new drug called vudalimab (also known as XmAb20717) helps people with certain advanced cancers. These cancers affect parts of the body like the ovaries, cervix, and prostate. The study has two parts. In the first part, small groups of 10 people with specific types of cancer will try the drug. If it works well, more people may join in the second part. The study is open-label, which means both the doctors and patients know they are taking the drug.

Key Points:

  • The study may last for several weeks, and patients will need to visit the study center regularly.
  • Patients must be at least 18 years old and have tried other treatments before joining.
  • People in the study should not be using other cancer treatments while participating.

People can join if they are 18 or older, have certain types of cancer, and have tried other treatments before. Pregnant or breastfeeding women cannot participate. The study hopes to find out if the drug can help shrink tumors and improve health.

Study details
    Ovarian Cancer
    Clear Cell Carcinoma
    Endometrial Cancer
    Cervical Carcinoma
    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

NCT05032040

Xencor, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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