Doxycycline is a medicine that may help protect against HIV (a virus that attacks the immune system) and STIs (sexually transmitted infections). This study tests how well doxycycline reaches body tissues like the rectum and vagina. Researchers hope to create a single-dose medication to prevent these infections.
If you join, you will be in the study for about 8 weeks. You will share your medical history and give samples of blood, urine, and fluids from the rectum or vagina. You may also need a small tissue sample taken (biopsy) from these areas. This helps researchers see how doxycycline works inside the body.
The study is looking for healthy volunteers aged 18-59 years who are willing to use condoms and who are not on certain medications or planning to relocate soon. Participants should not be pregnant.
- Study lasts about 8 weeks with sampling procedures.
- Healthy volunteers aged 18-59 are needed.
- Participants should avoid certain medications and not be pregnant.