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A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Hyaluronidase (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11)

Comparing patient preferences: Subcutaneous vs. IV Pembrolizumab in various cancers.

Recruiting
18 years and older
All
Phase 2

Pembrolizumab is a medicine used to treat different types of cancer. In this study, researchers want to see if people with cancer prefer getting pembrolizumab as a shot under the skin (called subcutaneous) with another substance, hyaluronidase, or through a needle in the vein (intravenous). This study does not test if one way is better than the other, it only asks for people’s preferences.

  • This study involves people with early stage or advanced solid tumors like melanoma, renal cell carcinoma, and non-small cell lung cancer.
  • Participants must be healthy enough, with a life expectancy of at least 3 months.
  • People who have had certain treatments or conditions, like recent surgery or active infections, cannot join.

The study does not involve any new treatments, just different forms of the same treatment, and there are no tests to see if one is better at fighting cancer. If you qualify and decide to join, you will share which method you prefer. This might help doctors understand how to make treatments more comfortable for patients in the future.

Study details
    Non-Small Cell Lung Cancer
    Renal Cell Carcinoma
    Melanoma

NCT06099782

Merck Sharp & Dohme LLC

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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