Study Purpose: This study checks if a new drug called ALKS 2680 is safe and works well for people with Narcolepsy Type 1. Narcolepsy is a condition that makes people very sleepy during the day and can cause cataplexy, where they suddenly lose muscle control. The study will see if people feel less sleepy and have fewer cataplexy episodes when taking ALKS 2680 compared to a placebo, which is a harmless pill that doesn't have the real medicine.

Eligibility: To join, you need to be between 18 and 70 years old, have a Body Mass Index (BMI) between 18 and 40, and have Narcolepsy Type 1. You also need to stop any other narcolepsy medications for 14 days before and during the study. If you have other major health problems, you might not be able to join.

• The study requires you to stop other narcolepsy medications for at least 14 days.
• Participants must be willing to follow the study rules and procedures.
• Eligibility is evaluated individually, especially for those with other health conditions.