This research study is looking at how well letrozole, a medicine that lowers estrogen in the body, works alone or with two chemotherapy drugs, paclitaxel and carboplatin, for treating a type of cancer called low-grade serous carcinoma. This cancer affects the ovaries, fallopian tubes, or peritoneum. Chemotherapy helps by either killing cancer cells or stopping them from growing. The study aims to see if taking letrozole alone is just as good as taking it with chemotherapy. Participants need to have a specific stage of cancer and must have had surgery to remove as much cancer as possible. They should be able to take oral medicine and meet certain health requirements. The study will last for several years, with check-ups every few months. Letrozole is taken daily, and chemotherapy is given every 3 weeks for up to 6 cycles.
- Study Duration: Follow-ups for up to 4 years.
- Treatment: Letrozole alone or with chemotherapy.
- Eligibility: Specific cancer stage, no prior chemotherapy.