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Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

Studying Talazoparib for breast cancer with specific genetic mutations.

Recruiting
18 years and older
Female
Phase 2

This study is testing a drug called Talazoparib for patients with a specific type of breast cancer. Breast cancer is a disease where cells in the breast grow out of control. Some people have a change in their DNA, called a BRCA mutation, which can cause cancer to spread to other parts of the body, called metastatic cancer. Talazoparib is a medication being studied to see if it can stop cancer cells from growing by blocking proteins called PARPs that help repair damaged DNA.

  • This study lasts several months and involves regular doctor visits.
  • Participants must have specific cancer mutations and cannot have used a similar drug before.
  • Patients are not paid but may receive free medication and health check-ups.

Before joining, make sure to discuss with your doctor, as there are specific health requirements and risks involved. Also, patients need to be at least 18 years old and cannot be pregnant or breastfeeding during the study.

Study details
    Breast Cancer

NCT03990896

Massachusetts General Hospital

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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