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A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease

Evaluating Vixarelimab for lung conditions like fibrosis and sclerosis.

Recruiting
18-85 years
All
Phase 2

This study checks how well a drug called vixarelimab works for lung diseases, specifically Idiopathic Pulmonary Fibrosis (IPF) and Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD). IPF is a disease where lung tissue gets scarred for unknown reasons, making it hard to breathe. SSc-ILD is lung scarring that happens with a disease where the skin and other organs become thick and hard. The study compares vixarelimab to a placebo, which is a fake treatment that looks like the real drug but doesn't have any active ingredients. Participants take part for 52 weeks, and if they complete this, they can join an additional 52-week phase with the actual drug.

  • The study lasts up to 104 weeks (2 years) if you join the optional phase.
  • You may continue your current treatments if stable and according to the study rules.
  • Participants should not have had a lung transplant or certain infections recently.

Deciding to participate in a study should be discussed with your doctor to ensure it's the right choice for your health condition.

Study details
    Idiopathic Pulmonary Fibrosis
    Systemic Sclerosis With Lung Involvement

NCT05785624

Genentech, Inc.

29 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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