This study tests a tool called **CIVO** (Comparative In Vivo Oncology), which helps understand how cancer treatments work inside a tumor. **Phase 0** means it's an early step in research. The study involves injecting tiny amounts of cancer drugs directly into tumors that are easy to reach and are already planned for surgery. The **CIVO device** uses a special marker called CIVO GLO to see where the drugs are injected. This tool helps find out which drugs might work well without causing bad side effects.

• The study requires patients to have surgery planned within 7 days after the CIVO injection.
• Participants must be 18 or older, and able to follow study visits and provide consent.
• Pregnant or breastfeeding women cannot join the study.

This study allows testing of up to eight different cancer drugs at once, which helps researchers find good treatment options quickly. It’s important for participants to know that the study involves injections and a surgery, and everyone can leave the study at any time if they choose.