The PREVENTABLE study is looking at whether a medication called atorvastatin, which lowers fat in the blood, can help older adults stay healthier. This study involves 20,000 adults who are 75 years or older, don't have heart disease or memory issues like dementia, and live in the community. Participants will either receive atorvastatin or a placebo (a pill that looks like the medicine but has no active ingredient) for up to five years. The study wants to see if atorvastatin can reduce the risk of death, dementia, and disability, as well as minor memory problems and heart issues.

• The study will take place over up to five years, with regular check-ins by phone and possibly in-person if needed.
• Participants will receive the study drug or placebo by mail every 90 days.
• Eligible participants should not have heart disease, memory issues, or have taken statins recently.

If you're interested, you can talk to a study site near you or participate remotely. It's important to know if atorvastatin is safe for you, so a doctor will help decide. Participants will have their physical and mental health checked throughout the study.