Crohn's disease (CD) is a condition where parts of your digestive system, like your small and large intestines, become swollen and red. This can cause stomach pain, diarrhea, and other symptoms. Scientists believe CD might be linked to certain factors like diet, antibiotics, or family history. In this study, doctors are using a special treatment called anti-TNF therapy to help reduce inflammation. TNF is a substance made by your body's white blood cells that can cause inflammation. The study, called CAMEO, aims to understand why some children with CD heal after this treatment while others do not. Kids aged 6-17 who are newly diagnosed with CD can join the study. They will receive treatment and have tests done for a year to check on their healing process. The study doesn't add extra risks beyond those of typical CD treatment. The study will take place across 27 clinical centers in North America and will last for five years. Doctors will use different tests, like blood, stool, and special scans, to measure healing.

• The study lasts for 5 years with a 1-year treatment phase.
• No extra risks involved beyond normal CD treatment.
• Participants need to be between 6-17 years and newly diagnosed with CD.