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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

Studying viral infections in children with transplants across multiple centers.

Recruiting
18 years and younger
All
Phase N/A

Study Overview: This study is looking at kids who have had or will soon have a transplant, like a bone marrow or organ transplant. Researchers want to see if checking for viruses before the transplant can predict if the child will get sick from a virus after the transplant.

Key Points:

  • Participants must be under 18 and planning to have a transplant or have had one recently.
  • Nasal swabs and blood samples will be collected at different times: when joining the study, 100 days after the transplant, and if the participant catches a virus.
  • Parents or guardians need to give permission, and kids must agree to participate if they are able.

Terms Explained:

  • Hematopoietic Cell Transplant (HCT): A procedure where a patient receives healthy blood-forming cells (stem cells) to replace their own damaged or diseased cells.
  • Solid Organ Transplant (SOT): Surgery to replace a failing organ, such as a kidney or liver, with a healthy one from a donor.
  • Respiratory Viral Infection (RVI): An infection in the lungs that can be caused by viruses like the flu or common cold.
Study details
    Hematopoietic Cell Transplant
    Solid Organ Transplant
    Respiratory Viral Infection

NCT05550298

Arkansas Children's Hospital Research Institute

11 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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