Image

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Comparing TAR-200 with Cetrelimab to chemoradiotherapy for bladder cancer.

Recruiting
18 years and older
All
Phase 3

This study aims to see if using TAR-200 with a medicine called cetrelimab helps people with muscle-invasive bladder cancer live longer without needing bladder removal, compared to regular treatment like chemotherapy (using strong medicines) and radiation (using high-energy rays). TAR-200 is a small, flexible device placed in the bladder to release medicine directly. Cetrelimab is given through an IV, which means it's put directly into a vein. Participants should be in good health, as shown by tests like blood and liver checks. They should not have cancer outside the bladder or too many cancer spots in the bladder. The study doesn't need bladder surgery, but there are some risks, like possible difficulty placing the TAR-200 device.

  • The study requires regular check-ups and tests for safety and effectiveness.
  • Participants must not be eligible or choose not to have bladder removal surgery.
  • Compensation may be provided for time and travel costs.
Study details
    Urinary Bladder Neoplasms

NCT04658862

Janssen Research & Development, LLC

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.