Image

First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

Join our study on DS-1062a for advanced solid tumors.

Recruiting
18 years and older
All
Phase 1

This study is testing a new medicine called DS-1062a on people with advanced solid tumors, like non-small cell lung cancer (NSCLC), who haven't been cured by other treatments. It's the first time this medicine is being used in humans. A solid tumor is a mass of tissue that can be cancerous or non-cancerous. The study has two parts:

  • Dose Escalation: Finding the safest dose of DS-1062a.
  • Dose Expansion: Checking the safety of DS-1062a in other tumors.

The study will last about 6 years and take place in the United States and Japan. People can stay in the study as long as they benefit from the treatment and don't have bad side effects or their disease worsens. A sub-study will compare the effectiveness of steroid vs. non-steroid mouthwash to prevent mouth sores from the treatment. About 76 people will join this part.

  • Study duration: approximately 6 years.
  • Locations: United States and Japan.
  • Sub-study involves about 76 participants.
Study details
    Hormone Receptor Positive Breast Cancer
    Triple Negative Breast Cancer
    Non-small Cell Lung Cancer

NCT03401385

Daiichi Sankyo Co., Ltd.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.