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NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)

Join a trial for boys with Duchenne Muscular Dystrophy.

Recruiting
4-14 years
Male
Phase 2

This study is testing a new treatment, NS-089/NCNP-02, for boys aged 4 to under 15 with Duchenne Muscular Dystrophy (DMD). DMD is a muscle disorder caused by certain genetic mutations. The study is for boys whose mutations can be fixed by skipping exon 44, a part of the gene. The medicine is given through an IV (a needle in the vein) once a week. There are two parts: Part 1 with 6 boys, and Part 2 adds 14 more boys.

Boys need to be able to walk by themselves and perform a simple stand-up test in less than 7 seconds. They should have been on a stable dose of glucocorticoid, a type of medicine, for at least 3 months. Boys who weigh less than 20 kg, have heart problems, or have recently had other treatments or surgeries cannot join.

  • The study lasts for two parts, with more boys joining in Part 2.
  • Participants receive weekly IV infusions.
  • Eligibility includes specific age, weight, and health conditions.
Study details
    Duchenne Muscular Dystrophy

NCT05996003

NS Pharma, Inc.

16 November 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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