Image

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

Researching new treatments for juvenile spondyloarthritis symptoms.

Recruiting
8-21 years
All
Phase N/A

Biologic Abatement and Capturing Kids' Outcomes is a study for children aged 8 to 21 who have juvenile spondyloarthritis (SpA), a type of arthritis affecting the spine. The study examines reducing or stopping TNFi (tumor necrosis factor inhibitor) therapy, a medication that helps control inflammation. Eligible kids must have had no disease activity for at least six months while on TNFi. The study is 12 months long, with check-ups every 3 months. Kids will be randomly placed in one of three groups: continuing the same TNFi dose, taking longer breaks between doses, or stopping TNFi. After 12 months, if no disease flare-ups occur, treatment plans can be adjusted with the doctor. Kids will be followed for 24 additional months to check long-term effects. The study excludes those with conditions like inflammatory bowel disease or uncontrolled uveitis.

  • Study length: 12 months, with follow-up for 24 months.
  • Check-ups every 3 months.
  • Eligibility: Kids aged 8-21 on TNFi with no active disease for 6 months.
Study details
    Juvenile Spondyloarthritis

NCT04891640

Children's Hospital of Philadelphia

10 October 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.