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Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol

Studying safe chemotherapy dosing (Carboplatin) with Iohexol contrast agent.

Recruiting
18 years and older
Male
Phase 1

This study is about finding the best way to give a cancer medicine called carboplatin. We use a special dye called iohexol to help doctors figure out the right dose. Carboplatin is used in chemotherapy, which is a type of treatment that stops cancer cells from growing. The study looks at how well different ways of measuring kidney function work for planning carboplatin doses. It also checks how carboplatin affects patients and if other tests can better predict kidney function.

  • The study requires 7-8 blood samples and lasts 3-4 weeks.
  • Only men aged 18 and older can join, and they need to have good overall health.
  • Those with allergies to certain dyes or foods, or specific health conditions, can't participate.

Participants will get iohexol and carboplatin through an IV (a needle in the vein) and will be checked on for a few weeks. This study is for men who will receive carboplatin as part of their cancer treatment, and it's important they can follow the study rules and finish all parts of the study.

Study details
    Malignant Solid Neoplasm

NCT03997370

NRG Oncology

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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