The study aims to test different treatments for people with chronic pain, which means pain that lasts for a long time. This includes pain from knee osteoarthritis (joint pain), chronic low back pain, and diabetic peripheral neuropathic pain (nerve pain due to diabetes). The study will compare different treatments and has specific guidelines for who can join. Participants need to have a specific level of pain, measured by a visual analog scale (VAS), and must have experienced daily pain for at least 12 weeks. They should not start any new non-drug therapies during the study and must stop other pain medications, except for emergency pain relief. However, people with certain heart issues, recent surgeries, or other serious health problems can't join. The study will collect results and share them as each treatment becomes available.

• Participants need to have had daily pain for at least 12 weeks.
• Participants must stop most pain medications during the study.
• People with serious health issues or recent surgeries cannot join.