This research study is trying to see if a new way to treat oropharyngeal cancer (a type of throat cancer) is as good as the usual treatment. The new method uses a special scan called *SPECT-CT* to guide where radiation should go, while the usual way gives radiation to both sides of the neck. *SPECT-CT* stands for **Single Photon Emission Computed Tomography**, which is a type of imaging that helps see inside the body more clearly.

People who can join this study must have a specific kind of throat cancer, and they must not have cancer spreading to the middle of the throat. They need to be able to get radiation treatments and possibly chemotherapy. They also need to agree to follow-up visits and complete surveys about their quality of life.

• The study involves radiation treatments and might include chemotherapy.
• Participants will need to have several scans and tests before starting.
• Participants will be asked to fill out surveys about their health and quality of life.