Image

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Examining Afimetoran's effectiveness and safety in treating active lupus.

Recruiting
18-70 years
All
Phase 2

This study looks at how well a drug called Afimetoran works for people with a condition called Systemic Lupus Erythematosus, or **SLE**. SLE is a disease where the body's defense system attacks its own tissues, causing problems like joint pain and rashes. The study compares Afimetoran with a **placebo** (a fake treatment) to see if it is safe and effective. For those who first get the placebo, they will get a chance to try Afimetoran later in the study.

To join, you must have been diagnosed with SLE at least 12 weeks before the study starts. You should test positive for certain antibodies (proteins in the blood), and have a disease activity score above a certain level. You cannot join if you have severe kidney problems caused by lupus or other specific conditions.

  • The study may last a long time, as it includes an extension period for more data collection.
  • Participants will need to visit the study site for tests and check-ups.
  • Risks or side effects of Afimetoran will be closely monitored.
Study details
    Systemic Lupus Erythematosus

NCT04895696

Bristol-Myers Squibb

15 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.