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A Clinical Study of MK-2870 Alone or With Chemotherapy to Treat Gastrointestinal Cancers (MK-9999-02A)

Study of MK-2870 for treating gastrointestinal cancers with or without chemotherapy.

Recruiting
18 years and older
All
Phase 1/2

This study is testing a drug called sacituzumab tirumotecan (MK-2870) for treating certain stomach and intestine cancers. Some of these cancers have spread to other body parts, while others can't be removed with surgery. The study aims to find out how safe the drug is and if it helps shrink or eliminate the cancer when used alone or with chemotherapy.

To join, you must have one of these cancers: colorectal cancer that can't be removed or has spread, advanced pancreatic cancer, or bile duct cancer. You also must have had some cancer treatment before and recovered from its side effects. You can't join if you've had serious eye problems or certain lung diseases, or if you've had another cancer treatment recently.

  • Study Length: Varies depending on individual response to treatment.
  • Visits Needed: Regular visits for monitoring and treatment.
  • Possible Risks: Side effects from the drug or chemotherapy.

Consider joining if you meet the conditions and are comfortable with the study requirements.

Study details
    Colorectal Cancer
    Pancreatic Ductal Adenocarcinoma
    Biliary Tract Cancer

NCT06428409

Merck Sharp & Dohme LLC

15 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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