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Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

Trial testing new HIV prevention vaccine in adults.

Recruiting
18-55 years
All
Phase 1

This study is testing a new HIV vaccine on adults without HIV. The vaccine uses special proteins and virus particles to help the body make antibodies. Antibodies are proteins that help fight infections. This study aims to see if the vaccine is safe and if it helps the body make these antibodies.

Participants must be adults aged 18 to 55 and in good health. They cannot be pregnant or have certain health conditions. Participants will have regular clinic visits to receive the vaccine and must fill out a daily symptom diary.

  • Study Duration: Participants will be involved through several clinic visits over a period.
  • Eligibility: Must be 18-55 years old and in good health.
  • Commitments: Regular clinic visits and symptom tracking.

Before joining, potential participants will have to understand the study and agree not to join another clinical trial. They must also use effective birth control during the study. The study excludes people with certain health conditions like severe asthma or recent vaccines. If interested, please ensure you meet all eligibility criteria and are willing to follow study procedures.

Study details
    HIV

NCT06332339

National Institute of Allergy and Infectious Diseases (NIAID)

12 October 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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