Study Overview: This study looks at stopping immunotherapy early for people with advanced melanoma, a type of skin cancer that can't be removed by surgery. They use special tests called PET/CT scans and tumor biopsies to help decide if it's safe to stop the treatment. The treatment involves drugs called anti-PD-1 therapies, which help the immune system fight cancer.
- Study Length: The study lasts up to 5 years with follow-ups every 3 months.
- Eligibility: You must have advanced melanoma and be receiving anti-PD-1 therapy.
- Risks: Possible side effects from stopping or continuing therapy; requires regular scans and biopsies.
Key Details: Patients will either stop or continue their treatment based on the scan and biopsy results. If the scan shows no active cancer, they may stop the treatment and be watched carefully. If the scan or biopsy shows active cancer, they continue the treatment. Regular follow-ups ensure they are monitored closely.