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A 2-Part First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of CMTX-101

Study to assess safety and effects of CMTX-101 in humans.

Recruiting
18 years and older
All
Phase 1

This study is testing a new medicine called CMTX-101. CMTX-101 is a type of medicine called a monoclonal antibody, which helps fight bacterial infections by breaking down protective layers called biofilms that bacteria form. This study has two parts. The first part will test the medicine on healthy adults, and the second part will test it on patients with a lung infection called community-acquired bacterial pneumonia (CABP). The main goals are to see if the medicine is safe, how it behaves in the body, and if it causes the body to make antibodies against it.

  • Study Length: Participants will receive one dose of CMTX-101 through an intravenous infusion, which takes 60 minutes.
  • Eligibility: Participants must be 18 or older, and females must use birth control during the study.
  • Risks: Those with certain medical conditions, like autoimmune diseases, or those who are pregnant, cannot participate.

You may be compensated for your time. Please consider the eligibility criteria and potential risks before deciding to participate, and consult with the study team for more details.

Study details
    Community-acquired Pneumonia
    Bacterial Pneumonia

NCT05629741

Clarametyx Biosciences, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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