The SYMPHONY-PE study is testing a new tool, called the Symphony Thrombectomy System, to help treat pulmonary embolism (PE). PE is when a blood clot blocks blood flow in the lungs. This study is checking if this tool is safe and works well. To join, you must have proof of a recent PE from a CTA scan (a special X-ray for blood vessels) and symptoms like shortness of breath or chest pain. You also need to be between 18 and 80 years old and agree to follow the study rules and visit schedule. People with certain health issues, such as severe kidney problems or recent major surgery, cannot join. If you had blood-clot dissolving medicine in the past two weeks, you also cannot participate.

• The study may involve multiple visits to the hospital.
• Participants will be monitored for safety and effectiveness of the treatment.
• Informed consent is required to take part in the study.