Coronary Microvascular Dysfunction (CMD) is a heart condition mostly in women, causing chest pain due to small blood vessel issues. This study is to understand how mental stress affects women with CMD compared to those without. The autonomic nervous system (ANS) manages involuntary actions like heart rate and breathing. Researchers will see how stress impacts these functions and the heart.

Participants will come from Emory Healthcare. They'll undergo tests like physical exams, blood work, stress and exercise tests, and heart imaging. They'll also use devices at home to track their heart functions, sleep, and stress for a week. The study aims to find new ways to treat CMD and prevent heart problems.

• Participants must be postmenopausal women aged 50 or older with symptoms but no major artery blockage.
• Involves stress testing and using monitoring devices at home for one week.
• Study helps improve understanding of stress impacts on CMD, potentially leading to new treatments.