Image

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

Evaluating different pain treatments to find the most effective option.

Recruiting
All
Phase N/A

This study is for veterans with chronic low back pain (cLBP). Chronic means the pain has lasted a long time, usually over six months. The study will compare different ways to treat this pain without surgery or medication. In the first step, participants try one of three treatments: continued care and monitoring (CCAM), internet-based pain self-management (Pain EASE), or an enhanced physical therapy program. If the first treatment doesn't work well, participants can choose from yoga, spinal manipulation therapy (SMT), or cognitive behavioral therapy (CBT) in the second step. The study will check how well these treatments reduce pain interference, which is how much pain affects daily activities, using a questionnaire called the Brief Pain Inventory (BPI).

  • The study lasts for one year, with follow-ups to see how well the treatments work over time.
  • Participants will be chosen from 20 VA centers and can receive treatment in-person or online.
  • Eligibility includes having cLBP for 6 months and being a veteran aged 18 or older.
Study details
    Chronic Low Back Pain

NCT04142177

VA Office of Research and Development

8 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.