This study looks at different ways to prevent peripheral neuropathy, a nerve disorder causing numbness or pain in arms and legs, from chemotherapy drugs like paclitaxel or docetaxel. The study uses a device called the Paxman Limb Cryocompression System, which involves cooling or squeezing the arms and legs. There are three groups: 1) cryocompression (cooling and squeezing), 2) continuous compression (steady squeezing), and 3) low cyclic compression (squeezing that comes and goes). Each group uses the device for about 90 minutes during chemotherapy sessions.

Key Points:

• The study lasts up to 52 weeks with different checkpoints (6, 12, 24, and 52 weeks) to see how the approaches work over time.
• Participants must be adults with certain solid tumor cancers, and they must not have had previous nerve-related chemotherapy or certain conditions like Raynaud's.
• Participants need to complete surveys and may have blood samples collected during the study.

This study aims to find the best method to prevent nerve problems from chemotherapy and to understand how these methods impact quality of life and treatment success. Participants will be monitored for any side effects and overall satisfaction with the treatment.