The study is for people with rheumatoid arthritis (RA), a condition where the body attacks its own joints, causing pain and swelling. Usually, people with active RA use a medicine called a TNFi-biologic, but if it doesn't help, they try other medicines, like non-TNFi biologics or targeted synthetic DMARDs (tsDMARDs). This study wants to see which medicine works better for RA patients who need a change. Patients will help decide which medicines work best based on their experience.

People can join the study if they have been using a TNFi-biologic for at least 3 months and still have active RA. They need stable doses of certain medications and insurance that covers the new treatments. People cannot join if they have used more than three biologic medicines before, have certain health issues, or are pregnant.

• The study compares two RA treatments to see which is better for patients.
• Participants need to have tried a TNFi-biologic for at least 3 months.
• Excludes people with specific health issues or more than three prior biologic treatments.