Study Summary: This research is about finding a better way to detect cervical cancer using self-collected samples for HPV testing. HPV, or human papillomavirus, is a common virus that can cause cervical cancer. Many people don't get screened for cervical cancer, which can lead to undetected pre-cancers turning into cancer. In this study, participants will collect their own vaginal samples for HPV testing, which might be more comfortable than a doctor's exam. The study will compare the results of self-collected samples to those collected by doctors.

Key Points:

• Participants will collect two samples themselves and have one collected by a doctor.
• The study involves one visit, and results are analyzed within 90 days.
• Eligible participants must be over 25 and have a cervix with recent abnormal screening results.

If you are pregnant, recently gave birth, or have certain medical conditions, you may not be eligible. This study is part of a larger effort by the National Cancer Institute (NCI) to improve access to cervical cancer screening and gain approval from the US Food and Drug Administration (FDA) for self-collection methods.