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Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer

Trying Low-Dose Interleukin-2 and Pembrolizumab for advanced lung cancer.

Recruiting
18 years and older
All
Phase N/A

This study looks at treating advanced lung cancer with two medicines: Interleukin-2 (IL-2), a protein that can help the immune system, and Pembrolizumab, a drug that helps the body fight cancer. In this study, patients with Stage IV non-small cell lung cancer (NSCLC) will be given both medicines to see if it helps their immune cells work better against cancer.

Key points to consider:

  • This is an early phase 1 study, which means it is in the beginning stages of research.
  • The treatment involves a combination of IL-2 and Pembrolizumab over several weeks with follow-up checks.
  • Patients need to be 18 years or older and have not had previous treatments for their advanced lung cancer.

During the study, IL-2 will be given twice daily for three weeks, and Pembrolizumab will continue either every three or six weeks. After the initial treatment, there is a follow-up for 6 weeks. This study aims to see if this combination is safe and if it helps in treating lung cancer. Participants need to meet specific health criteria to join.

Study details
    Lung Non-Small Cell Carcinoma
    Stage IV Lung Cancer AJCC v8
    Stage IVA Lung Cancer AJCC v8
    Stage IVB Lung Cancer AJCC v8

NCT05493566

Emory University

13 December 2024

Step 1 Get in touch with the nearest study center
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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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