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A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

Join a study on Milvexian for stroke or TIA recovery.

Recruiting
40 years and older
All
Phase 3
Study of Milvexian for Stroke Prevention This study investigates if a medicine called milvexian can help prevent strokes in people who have recently had a stroke or a specific kind of stroke warning called a Transient Ischemic Attack (TIA). A stroke happens when blood flow to the brain is blocked, causing brain damage. TIA is a short-term blockage with no lasting damage. Key Points:
  • The study lasts until a few days after the last dose of milvexian.
  • Participants are required to start the study within 48 hours after their stroke or TIA.
  • Women must not be pregnant or breastfeeding during the study.
To join, participants must meet certain conditions like having a low National Institute of Health Stroke Score (NIHSS), which measures the severity of a stroke, and be taking low-dose aspirin. People with certain health issues, such as previous brain bleeding or liver disease, cannot participate. It's important to know the study might involve risks, such as possible side effects from milvexian. Participants will be randomly assigned to take either milvexian or a placebo, which is a harmless pill that doesn't contain medicine, to see if milvexian works better.
Study details
    Ischemic Stroke; Ischemic Attack
    Transient

NCT05702034

Janssen Research & Development, LLC

8 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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