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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

Testing the safety and effectiveness of RGN-259 eye drops for NK.

Recruiting
18 years and older
All
Phase 3

This study aims to test the safety and effectiveness of RGN-259 eye drops compared to a placebo (a treatment with no active drug) for treating Neurotrophic Keratopathy (NK). NK is a disease that affects the cornea, the clear front part of the eye, due to damage to the eye's nerve supply. This damage leads to a lack of feeling in the eye, causing problems like reduced tear production and poor healing of the cornea.

To join the study, you must be 18 or older, provide consent, and meet specific eye health criteria. You should not have any conditions or recent surgeries that could interfere with the study. Women should use birth control, and both men and women must agree to avoid pregnancy during the study.

Key Points to Consider:

  • The study requires multiple visits to the study center.
  • Participants will be given either the RGN-259 eye drops or a placebo.
  • Some risks may include irritation or discomfort from the eye drops.
Study details
    Neurotrophic Keratopathy

NCT05555589

ReGenTree, LLC

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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