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Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

Exploring Belumosudil and Rituximab for treating chronic graft-versus-host disease.

Recruiting
18 years and older
All
Phase 2

This study is looking at two medicines, **belumosudil** and **rituximab**, to see if they are safe and helpful for people with a condition called chronic Graft-Versus-Host Disease (**cGVHD**). cGVHD happens when donated stem cells attack the body. This is a Phase 2 study, which means it is checking how well these medicines work and if they are safe. It is called "open-label" because both the doctors and the patients know what treatment is being given.

To join the study, you must be having your first treatment for cGVHD with medicine that affects the immune system. You should have good blood health and not have used certain medicines for more than 10 days. People with certain infections or heart problems cannot join.

  • The study involves taking belumosudil and rituximab.
  • There will be multiple visits to the study center for check-ups.
  • Participants should consider their health to see if they meet the criteria.
Study details
    Chronic Graft Versus Host Disease

NCT06046248

Northside Hospital, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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