Study Overview: This study is about finding better ways to prevent strokes in people with narrow brain arteries. A stroke happens when blood flow to the brain is stopped. The study will compare different medicines to see which works best. These medicines are called anti-coagulants (like rivaroxaban) and anti-platelets (like ticagrelor and clopidogrel). Anti-coagulants help prevent blood clots, while anti-platelets stop platelets (tiny blood cells) from sticking together.

Eligibility: Participants must have had certain symptoms or strokes due to narrowed brain arteries, be at least 30 years old, and able to take pills. Some people must also have conditions like diabetes or a history of heart issues.

Exclusions: People who have had certain treatments like stenting, tumors, or uncontrolled high blood pressure cannot join. Also, those with severe liver issues, active bleeding, allergies to study drugs, or those on conflicting treatments are not eligible.

• This study lasts for 1 year with regular check-ups.
• You must be able to travel for visits and follow-ups.
• No specific mention of compensation is provided.