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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Exploring blood-thinner treatments for brain artery narrowing.

Recruiting
30 years and older
All
Phase 3

Study Overview: This study is about finding better ways to prevent strokes in people with narrow brain arteries. A stroke happens when blood flow to the brain is stopped. The study will compare different medicines to see which works best. These medicines are called anti-coagulants (like rivaroxaban) and anti-platelets (like ticagrelor and clopidogrel). Anti-coagulants help prevent blood clots, while anti-platelets stop platelets (tiny blood cells) from sticking together.

Eligibility: Participants must have had certain symptoms or strokes due to narrowed brain arteries, be at least 30 years old, and able to take pills. Some people must also have conditions like diabetes or a history of heart issues.

Exclusions: People who have had certain treatments like stenting, tumors, or uncontrolled high blood pressure cannot join. Also, those with severe liver issues, active bleeding, allergies to study drugs, or those on conflicting treatments are not eligible.

  • This study lasts for 1 year with regular check-ups.
  • You must be able to travel for visits and follow-ups.
  • No specific mention of compensation is provided.
Study details
    Intracranial Arteriosclerosis
    Stroke

NCT05047172

University of Florida

8 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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