Sepsis is a serious condition where the body responds severely to an infection. The goal of this study is to see if using a special plan, called the Prehospital Sepsis Protocol (PRESS), can help Emergency Medical Services (EMS) workers identify and treat sepsis faster before patients reach the hospital. This might help doctors in the Emergency Department (ED) give antibiotics, which are medicines that kill bacteria, more quickly. The study will be done at three different places, each with an EMS team and a hospital working together.

The EMS team will use a specific tool to check for signs of sepsis, like low blood pressure or fast breathing, and call the hospital if they think someone has sepsis. This early warning could help doctors be ready to treat the patient as soon as they arrive. The study will look at whether this process reduces the time it takes to start treatment in the hospital.

• The study will include both a baseline and an intervention phase.
• EMS teams will be trained on how to use the PRESS protocol.
• The study might help improve the speed of sepsis treatment in hospitals.