The LOWER study is looking at a medication called lomitapide. This medicine is used to see how safe and effective it is over a long time. The study wants to know if doctors are following the safety checks recommended when they give lomitapide. This study is open to people of all ages, even kids. Everyone must agree to be part of the study and follow the rules. If you are 7 years or older, you need to sign a special form to show you agree. If you're younger, a parent or guardian must give permission. You cannot join if you are already in another drug study or using lomitapide in a special trial. You also cannot be using another new drug that is not approved in your country. If you stop using the new drug, you might still join.

• The study is long-term and looks at the safety and effectiveness of lomitapide.
• Participants can be of any age but must agree, and if children, parents must approve.
• Cannot join if involved in other drug trials or using unapproved drugs.