Image

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Checking TN-201 safety in adults with HCM due to MYBPC3 mutation.

Recruiting
18-75 years
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

This study is for adults with a specific heart condition called nonobstructive hypertrophic cardiomyopathy (nHCM). This condition happens when the heart muscle becomes too thick. This study looks at how safe and tolerable a new drug, TN-201, is for people with a gene change called MYBPC3 mutation. Participants will get one dose of the drug and be checked for five years. The study aims to see how the drug affects the body.

Eligibility: To join, you must have the MYBPC3 mutation, a heart condition without blockages, and a working device to help your heart. You also need certain heart function levels and symptoms.

  • This is a long-term study, lasting 5 years.
  • Participants will receive the active drug once.
  • There are specific requirements to join, like having certain heart conditions and devices.

Consider joining if you meet the eligibility criteria and are comfortable with the study's length and conditions. There are no details about compensation or specific risks in the description provided.

Print
Study details
    Hypertrophic Cardiomyopathy

NCT05836259

Tenaya Therapeutics

30 November 2024

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.