Sepsis is a serious condition caused by the body's response to an infection. In hospitals, patients with sepsis receive fluids to help them recover. There are two main types of fluids: normal saline and balanced crystalloids. This study aims to find out which type of fluid is better for patients. An algorithm (a kind of computer program) helps doctors decide which fluid to use based on patients' vital signs like heart rate and blood pressure. Patients who might benefit more from balanced crystalloids are placed in a special group called Group D. If a doctor orders normal saline for a Group D patient, a computer alert will suggest using balanced crystalloids instead.

• The study takes place in 6 Emory hospitals.
• Only adult patients in the emergency department are included.
• Doctors will receive alerts if balanced crystalloids might be better.

Participants will be monitored for up to 30 days or until they leave the ICU (Intensive Care Unit). The study's findings could change how fluids are used in hospitals to treat sepsis, potentially saving lives.