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A Study to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution in Patients With Dry Eye Disease

Evaluating a new eye drop for dry eye safety and effectiveness.

Recruiting
18 years and older
All
Phase 2

This study tests a new eye drop for dry eye disease, called *recombinant human nerve growth factor (rhNGF)*. The study checks if the eye drop helps more than a placebo (a treatment with no active medicine). People in the study will put one drop in each eye three times a day for 4 weeks. There are 5 visits over 8 weeks, where doctors check your eyes and ask questions. Dry eye disease is when eyes feel dry, sore, or like something is in them.

  • Study lasts for 8 weeks with 5 visits to the clinic.
  • Participants must use the eye drops three times daily for 4 weeks.
  • Participants must be 18+ and have had dry eye for over 6 months.

If you choose to join, you must be able to follow study instructions and cannot have eye infections or other serious eye problems. Also, you cannot be pregnant or plan to become pregnant during the study. The goal is to see if the new eye drops are safe and help treat dry eye symptoms better than a placebo. Before joining, you must read and sign a consent form to understand the study and agree to take part.

Study details
    Dry Eye Disease

NCT06244316

Dompé Farmaceutici S.p.A

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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