This study is for women with ovarian and endometrial cancer that has returned. It is a Phase Ib trial, meaning it is early testing to find the safest dose of two drugs, M1774 and ZEN-3694, when used together. These drugs may help stop tumor growth by blocking certain enzymes needed for cancer cells to grow.

The study has two parts. In Part I, the researchers want to find out the highest dose patients can handle without bad side effects. In Part II, they will look at how well the drugs work and how safe they are, especially in people with specific gene changes.

Participants will take the medicines by mouth and may have some tests like ECGs (a heart test) and scans (like x-rays or MRIs) to see how the treatment is working. After finishing the study, participants will be checked every few months for up to five years.

• The study involves taking pills and may include regular blood tests and scans.
• You must be at least 18 years old and able to swallow pills.
• If you have certain medical conditions or are pregnant, you cannot join.

If you are interested, talk to your doctor to see if this study is right for you.