This study is looking at how to best treat a lung infection caused by Mycobacterium avium complex (MAC), a type of bacteria. People usually take strong medicine called antibiotics to fight this infection. The study will compare taking two antibiotics, azithromycin and ethambutol, versus three antibiotics, which includes rifampin too. The goal is to see if taking two drugs is just as good but with fewer side effects. Side effects can be upset stomach, tiredness, and in rare cases, problems with eyes, hearing, or blood. The study will last 18-24 months and involves routine doctor visits to check how well the treatment is working and any side effects.
- Study Duration: 18-24 months with routine visits
- Participants will either take 2 or 3 antibiotics
- Monitors treatment effectiveness and side effects
To join, you must be over 18, have a positive MAC culture, and meet specific health criteria. You can't join if you have conditions like cystic fibrosis or HIV, or if you've had certain treatments recently. This study helps find better ways to treat MAC infections.