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Incremental Hemodialysis: The TwoPlus Trial

Join our TwoPlus Trial to explore incremental hemodialysis benefits.

Recruiting
18 years and older
All
Phase N/A
Incremental Hemodialysis: The TwoPlus Trial

This study is looking at two types of hemodialysis, a treatment to clean the blood when the kidneys don't work well. We are comparing incremental hemodialysis (starting with fewer sessions) with conventional hemodialysis (standard sessions) for people with new kidney problems and some remaining kidney function. A total of 350 patients and 140 caregivers will join. Caregivers are people who help patients, like family members. The study lasts about 2 years.

Doctors want to see if starting with fewer hemodialysis sessions helps patients feel better, have more energy, and affects caregivers' stress. They will also look at how long people live, hospital visits, and if their kidneys keep working.

  • Study lasts for about 2 years.
  • 350 patients and 140 caregivers will participate.
  • Both patients and caregivers will be checked during the study.

Who can join? Patients over 18 who've had up to 36 hemodialysis sessions and have some kidney function left. Caregivers must also be over 18 and the main carer chosen by the patient.

Please note, if you are pregnant or have certain health issues, you may not be eligible to join.

Study details
    End-Stage Kidney Disease

NCT05828823

Wake Forest University Health Sciences

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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