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Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

Study comparing Sugammadex and Neostigmine for kids' appendix surgery recovery.

Recruiting
2-17 years
All
Phase 4

Study Purpose: This research compares two medicines, sugammadex and neostigmine, used to help children recover from muscle relaxation after surgery for appendicitis. The study aims to see which medicine helps kids feel better faster and has fewer side effects.

Study Design: Children aged 2-17 having laparoscopic (small camera) surgery for appendicitis at a single hospital will be in this study. Each child will be randomly assigned to receive either sugammadex or neostigmine to help their muscles recover after the surgery. The anesthesiologist, who helps manage pain and sleep during surgery, will know which medicine is given to make the best decisions for each patient.

  • The study takes place at one hospital, Children's Healthcare of Atlanta-Egleston.
  • Only children with appendicitis and no allergies to the study drugs can participate.
  • Parents must agree to join and sign a consent form.

Understanding how these medicines work can help doctors provide better care for children after surgery. The study will look at how quickly children can eat and how well they recover overall.

Study details
    Appendicitis
    Surgery

NCT05256901

Emory University

10 October 2024

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