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A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Testing BI 764532 doses in DLL3-positive lung and neuroendocrine tumors.

Recruiting
18 years and older
All
Phase 1

This study is for adults with small cell lung cancer or other neuroendocrine cancers that show a tumor marker called delta-like 3 (DLL3). These are advanced cancers where other treatments didn't work. The study is testing a new medicine, BI 764532, which might help the immune system fight cancer. BI 764532 is given for the first time to people, so there's no previous data on it. Participants will get BI 764532 weekly or every 3 weeks, for up to 3 years, and will visit the study site about 20 times. These visits help doctors check if the treatment is working and watch for any side effects.

  • **Study Length**: Treatment can last up to 3 years with around 20 site visits.
  • **Treatment**: BI 764532 is an experimental drug, given weekly or every 3 weeks.
  • **Eligibility**: For advanced cancer patients who have no other treatment options.
Study details
    Patients With Small Cell Lung Carcinoma and Other Neoplasms

NCT04429087

Boehringer Ingelheim

11 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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