Anhedonia is a condition where people find it hard to feel pleasure. This study is about testing a medicine called L-DOPA for people with depression and high inflammation (swelling in the body). It's an 8-week research where participants will either get L-DOPA or a placebo (a fake pill to compare effects). A total of 70 men and women, aged 25-55, will take part. They'll do lab tests, medical check-ups, and MRI scans (a type of body scan) during the study. The full study lasts about 10 to 12 weeks.
- Time Commitment: The study lasts 8 weeks, plus extra time for preparation and follow-up, totaling 10 to 12 weeks.
- Eligibility: Participants must be 25-55 years old, have depression with high inflammation, and not be on antidepressants 4-8 weeks before starting.
- Activities: Participants will undergo various tests, including motivation and motor tasks, and MRI scans.
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