The LEGEND Study is testing a new treatment called EG-70 for people with bladder cancer. Bladder cancer is when bad cells grow in the bladder, which is the organ that holds urine. EG-70 is a special kind of treatment known as gene therapy, which is designed to help the body fight the cancer right where it is, in the bladder. This study has two parts: Phase 1 checks if EG-70 is safe and Phase 2 checks how well it works.
In the study, patients who have tried a treatment called BCG but it didn't work, or who haven't had enough BCG, can join. BCG is a therapy that helps the body fight cancer. People in the study will get the EG-70 treatment for about one year, with regular check-ups to see how they are doing.
- Participants will undergo up to four 12-week cycles of EG-70 treatment.
- There are eligibility requirements related to previous cancer treatments and health conditions.
- Patients must be willing to follow all the study rules and give consent to participate.
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