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A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

Exploring new ways to manage knee pain from osteoarthritis.

Recruiting
18 years and older
All
Phase 3

Knee Osteoarthritis (KOA) is a condition that causes pain and stiffness in the knee joint. It affects many older adults and is a big health problem worldwide. Surgery is not always the best choice because it can still leave people in pain. This study aims to find better ways to treat KOA without surgery or opioids, which are strong pain medicines.

The study will have two phases. In Phase 1, researchers will try different non-opioid medicines and behavioral treatments. If more help is needed, Phase 2 will offer other medical procedures. The study will help understand which treatment works best for different people.

  • The study involves two phases with different treatments.
  • Participants should expect to undergo a randomized controlled trial.
  • Women who are pregnant or plan to become pregnant should not participate.

To join the study, you must be over 18, have knee pain, and meet specific health criteria. People with certain health conditions or who have had specific knee treatments recently might not be eligible. Participants are expected to use reliable birth control methods if of childbearing potential.

Study details
    Knee Osteoarthritis

NCT04504812

Johns Hopkins University

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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