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Reduced Intensity Fludarabine and TBI Prior to Haplo-Identical Transplantation

Testing a gentler pre-transplant treatment for partial match donors.

Recruiting
18 years and older
All
Phase N/A

This study is testing a new way to do a stem cell transplant, called RIC HIDT. In this trial, patients will receive a medicine named Fludarabine and a type of radiation called TBI (Total Body Irradiation) before getting the transplant. The transplant uses cells from a family member whose blood matches at least half of yours. The goal is to see if this new method is safe and works well.

  • The study requires a related donor whose blood matches yours at least 3 out of 6 possible ways.
  • Participants need to have a blood cancer that needs a transplant and have a good performance status (KPS ≥ 70%).
  • There are health requirements you must meet, like having a good heart and lung function.

If you qualify, you will receive the new transplant treatment and be monitored closely. The study checks how your body responds to the treatment. Consider the time commitment and whether you meet all health criteria. There might be risks involved, and it's important to discuss these with your doctor before deciding.

Study details
    Hematologic Malignancy

NCT05417971

Northside Hospital, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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